Wednesday, July 11, 2012

Alzheimers gene

  • Two decades ago, researchers began discovering rare gene mutations that cause Alzheimer's disease in all who inherit them. Now, they have found the opposite: a mutation that prevents the devastating brain disorder.
  • (New York Times)
  • NEW YORK (Reuters) - A gene that causes the rare, early-onset form of Alzheimers disease can also carry a mutation that produces the opposite effect, staving off the devastating illness, scientists announced on Wednesday.
  • (msnbc.com)
  • Alzheimer˜s disease is a progressive neurodegenerative disease associated with the production and accumulation of beta-amyloid peptides produced by cleaving bits off the APP.
  • (Phramalive.com)
  • Bapineuzumab is one of the largest bets ever placed in the field of Alzheimers disease.
  • (Newser)
  • Three genetic markers for familial (or early-onset) Alzheimer's have been discovered so far: mutations in the genes for presenilin-1 and -2 and the amyloid precursor protein.
  • (familypracticenews.com)
  • The protein, known as amyloid-beta, codes for the gene able to activate Alzheimer's disease; this dangerous culprit (amyloid-beta) is a prion, which is a misfolded protein that is able to convert normal proteins into more prions.
  • (Examiner)
  • Open access helped draw funding to expand the program into genetic testing, said Wojcicki, also chief executive officer of Mountain View, California-based gene-testing company 23andMe.
  • (Waterbury Republican-American)
  • He says researchers dont know exactly how Resveratrol works, but they believe it can activate a gene associated with brain aging.
  • (KING-5)
  • Open access helped draw funding to expand the program into genetic testing, said Wojcicki, also chief executive officer of Mountain View, California-based gene-testing company 23andMe.
  • (San Francisco Gate)

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